@conference {40746,
	title = {Genetic markers in Inverdale (FecX) sheep},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {55},
	year = {1995},
	month = {Jan},
	pages = {307-309},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	abstract = {The Inverdale gene (FecX) is carried on the sheep X-chromosome.  Males carrying the Inverdale gene always pass a copy to their daughters,  but not to their sons. Females carrying a single copy will pass the  gene on to half of their offspring (both male and female). Progeny  testing to determine which rams carry the gene, and which offspring have  inherited, is time-consuming. Successful management of the Inverdale  gene will require a simple, quick inexpensive test to distinguish  carriers and non-carriers.    A research programme has been initiated to develop a DNA test using DNA  markers which will identify carrier animals at birth. Our initial  strategy to find suitable markers was to build a map of genes and DNA  markers on the sheep X-chromosome as a framework for looking for the  Inverdale gene. We have determined the relative positions of twenty  genes and DNA markers on the X-chromosome by looking at the pattern of  inheritance of the X-chromosome markers in sheep pedigrees established  in flocks at Invermay and Tuatapere. We estimate that 80\% of the  chromosome has been eliminated in our search to the Inverdale gene.  Efforts are now directed towards identifying the particular region of  DNA in which the Inverdale gene might lie. Suitable markers must be  close enough to the Inverdale gene to be always inherited with  Inverdale. Once such markers are identified a test can be developed to  determine the Inverdale status of animals. Adaptation of the current  techniques will enable DNA to be isolated from a few drops of blood, a  mouth swab, or the ear tissue from a newborn animal.   },
	issn = {1176-5283},
	author = {Galloway SM and Hanrahan V and Potts MP and Hill DF}
}
