@conference {41402,
	title = {Protein concentration in the rat maternal diet programs appetite and glucose metabolism in the offspring},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {63},
	year = {2003},
	month = {Jan},
	pages = {45-48},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	address = {Queenstown},
	abstract = {The effect of dietary protein concentration throughout gestation and lactation on maternal appetite, and appetite and glucose metabolism of the offspring, was investigated. Female Sprague-Dawley rats were fed diets containing either 20\% whey protein (control; C, n=20) or 5\% whey protein (low-protein; LP, n=30) through gestation and lactation. LP mothers gained less weight during gestation (88 vs. 136 g, SED=18, P<0.01), and consumed less food during lactation (451 vs. 902 g, SED=77, P<0.001). C offspring were heavier at birth (6.5 vs. 5.3 g, SED=0.5, P<0.05), consumed more food (273 vs. 178 g, SED=15, P<0.05), and gained weight more rapidly (5.9 vs. 3.7 g/day, SED=0.4, P<0.001) than LP offspring. LP offspring had lower fasted blood glucose at 40 (2.2 vs. 3.5 mmol/L, SED=0.4, P<0.01) and 50 (2.9 vs. 4.8 mmol/L, SED=0.2, P<0.001) days of age and were more sensitive (P<0.001) in response to a glucose challenge at 30 (498 vs. 615 mmol/L min, SED=24), 40 (557 vs. 700 mmol/L min, SED=24) and 50 (535 vs. 781 mmol/L min, SED=44) days of age. These results show that maternal dietary protein concentration during gestation and lactation programs appetite and glucose metabolism in the offspring. },
	issn = {1176-5283},
	author = {Barnett MPG and Harris PM and Cooper GJS}
}
