@conference {40747,
	title = {Inverdale as a model},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {55},
	year = {1995},
	month = {Jan},
	pages = {310-311},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	abstract = {The Inverdale gene (FecX) is extraordinary. Located on the X-  chromosome, it increases ovulation rate in the heterozygous state, but  in the homozygote the ewe has undeveloped or "streak" gonads and is  sterile. The phenotype is almost certainly due to the action of the  gene in early embryonic/foetal development.    The Inverdale may be valuable model for investigation of similar  phenotypes in other species, especially the human female.  Identification of the gene itself will enable substantial progress in  understanding mechanisms of ovarian and follicle development. However,  even without knowledge of the specific gene function, there are the  areas where the phenotype itself may be of real value. Two such areas  are the "tumour-like" structures in the homozygote as a model for  ovarian tumours and the "steroid-free" environment of the homozygote as  a model for investigating the regulation of seasonality in sheep.   },
	issn = {1176-5283},
	author = {Fennessy PF}
}
